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1.
Org Biomol Chem ; 21(44): 8942, 2023 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-37916526

RESUMO

Correction for 'An efficient metal free synthesis of 2-aminobenzothiozoles - a greener approach' by Krithika Ganesh et al., Org. Biomol. Chem., 2023, 21, 564-568, https://doi.org/10.1039/D2OB01981G.

2.
Org Biomol Chem ; 21(3): 564-568, 2023 01 18.
Artigo em Inglês | MEDLINE | ID: mdl-36538019

RESUMO

A facile one-pot, metal-free method for the synthesis of 2-aminobenzothiazoles was developed, which includes an initial reaction of electron-deficient 2-haloanilines with aromatic isothiocyanates and the subsequent intramolecular cyclization of the resulting thioureas through the SNAr mechanism. This one-pot, atom-economical, robust, and scalable method avoids the use of reagents such as acid chlorides and Lawesson's reagent that are difficult to handle.


Assuntos
Metais , Tioureia , Estrutura Molecular , Indicadores e Reagentes , Ciclização
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